Table 1 Patient demographics
Dex (−) (n = 6) | Dex 1 day (n = 12) | Dex multiday (n = 6) | |
|---|---|---|---|
Age (year) | 67.3 (58–73) | 67.0 (57–79) | 69.5 (57–76) |
Sex (male/female) | 5/1 | 12/0 | 3/3 |
PS (0/1/2) | 5/1/0 | 10/1/1 | 6/0/0 |
Body surface area (m2) | 1.8 (1.5–2.0) | 1.7 (1.5–1.8) | 1.6 (1.4–1.8) |
BMI (kg/m2) | 22.9 (19.8–28.1) | 21.2 (15.9–27.5) | 24.7 (19.3–30.0) |
Creatinine clearance (mL/min) | 94.5 (62.3–125.1) | 99.8 (55.6–143.7) | 98.5 (65.9–143.8) |
Total bilirubin (mg/dL) | 0.53 (0.4–0.8) | 0.63 (0.3–1.4) | 0.72 (0.5–1.3) |
AST (IU/L) | 24.7 (12–31) | 22.0 (10–32) | 18.3 (15–21) |
Concomitant medications | |||
Oral 5HT3 receptor antagonists (%) | 83.3 | 33.3 | 100 |
Dopamine antagonists (%) | 50 | 33.3 | 50 |
Drugs reported leucopenia (%) | 50 | 41.7 | 33.3 |
Purgative medicine (%) | 50 | 50 | 50 |