Fig. 3From: Drug interaction between methotrexate and salazosulfapyridine in Japanese patients with rheumatoid arthritisChanges of serum MMP-3 and cytokine levels. a The left figure shows serum MMP-3 (□) levels (mean ± SD (bars), n = 10) at the conclusion of SASP/MTX combination therapy (baseline, 0 weeks), and at 12 and 24 weeks after withdrawal of SASP. b The right figure shows serum TNF-α (●) and the serum IL-6 (○) levels (mean ± SD (bars), n = 4) at the conclusion of SASP/MTX combination therapy (baseline, 0 weeks), and at 4, 8 and 12 weeks after withdrawal of SASP. Comparisons were made by one-way repeated measures ANOVA with post hoc Tukey’s testBack to article page