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Table 3 Comparison of the incidence of adverse events between the prophylactic and regular groups in the entire study population

From: Safety profile of prophylactic rescue dosing of immediate-release oral opioids in cancer patients

Adverse event

Prophylactic rescue

Regular rescue

P value

n = 68

n = 35

Somnolence, n (%)

14 (20.6)

5 (14.3)

0.59a

Nausea, n (%)

15 (22.1)

6 (17.1)

0.62a

Constipation, n (%)

13 (19.1)

7 (20.0)

1.00a

Urinary retention, n (%)

1 (1.5)

1 (2.9)

1.00a

Delirium, n (%)

3 (4.4)

3 (8.6)

0.40a

Pruritus, n (%)

0 (0)

1 (2.9)

0.34a

  1. aFisher’s exact test