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Table 4 Apparent permeability coefficient of Rho123 and inulin across the middle intestinal tissues of control rats

From: Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies

 

Papp (× 10−6 cm/s)

m-s

s-m

ER

Rho123

2.14 ± 1.21

4.11 ± 2.85

1.92

inulin

1.40 ± 1.27

1.08 ± 0.86

0.771

  1. Values are mean ± SD of three rats
  2. m-s mucosal to serosal, s-m serosal to mucosal, ER efflux ratio, Papp apparent permeability coefficient, Rho123 rhodamine 123
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Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

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