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Table 3 Factors influencing the occurrence of thromboembolism

From: Risk factors for thromboembolism during first-line treatment of patients with unresectable advanced or recurrent colorectal cancer: a retrospective short study

 

Number of patients

Occurrence of thromboembolism, yes

Univariate analysis

Multivariate analysis

Model 1

Model 2

OR

95% CI

P-valuea)

OR

95% CI

P-value

OR

95% CI

P-value

Sex (female)

76

9

1.12

0.39–3.17

0.815

      

Age (65 years)

110

15

2.01

0.65–7.44

0.228

      

Primary lesion (Rectum)

61

7

1.05

0.33–3.02

1.000

      

Metastasis in other organs, yes

131

17

2.23

0.60–12.44

0.287

      

Comorbid cardiac disease, yes

5

2

5.68

0.45–53.13

0.096

      

CV port expansion, yes

155

20

inf

0.81–inf

0.080

      

Use of VEGF inhibitors, yes

134

12

0.46

0.16–1.39

0.110

0.48

0.18–1.31

0.153

   

Use of EGFR inhibitors, yes

45

8

2.19

0.72–6.34

0.110

   

2.07

0.76–5.60

0.153

Risk factors for occurrence of thromboembolism1

70

14

4.26

1.44–14.30

0.003

4.17

1.51–11.50

0.006

4.17

1.51–11.50

0.006

  1. a)Fisher’s exact test
  2. OR Odds ratio, 95% CI, 95% confidence interval, Inf Infinite, CV Central venous, VEGF Vascular endothelial growth factor, EGFR Endothelial growth factor receptor