Table 4 Stability of lacosamide in breast milk and plasma
Stability (% remaining) (Mean ± S.D., n = 6) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Concentration (ng/mL) | 24 h (4 °C) | 1 month (− 30 °C) | Freeze–thaw (− 30 °C and room temperature, 3 cycles) | |||||||
Breast milk | 1.25 | 112.7 | ± | 9.8 | 107.9 | ± | 2.4 | 106.5 | ± | 9.3 |
80 | 106.6 | ± | 6.3 | 101.9 | ± | 2.9 | 102.2 | ± | 7.8 | |
Plasma | 1.25 | 108.1 | ± | 7.6 | 107.6 | ± | 6.9 | 111.3 | ± | 6.5 |
80 | 106.0 | ± | 6.6 | 112.5 | ± | 5.9 | 108.2 | ± | 4.3 | |