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Table 3 Quantitative determination of the medicinal ingredients in the simple suspensionsa

From: A study on the chemical stability of cholesterol-lowering drugs in concomitant simple suspensions with magnesium oxide

Formulation

Without MG (%)

With MG (%)

After 10 min

After 5 h

After 10 min

After 5 h

AS

99.9 ± 3.2

94.2 ± 0.9

96.3 ± 2.2

91.7 ± 4.6

PS

100.5 ± 2.7

101.9 ± 3.4

96.4 ± 3.1

94.3 ± 3.4

RSb

97.6 ± 1.4

92.8 ± 1.9

95.3 ± 0.7

68.9 ± 6.8

SS

98.2 ± 0.9

96.4 ± 0.3

88.2 ± 1.0*

86.4 ± 2.1

(98.4 ± 1.9)

(97.7 ± 1.6)

(88.3 ± 2.1)*

(88.8 ± 2.5)

EZ

104.7 ± 1.7

103.9 ± 2.3

98.6 ± 2.0*

99.9 ± 1.5

(100.6 ± 1.0)

(99.6 ± 0.8)

(98.2 ± 2.3)

(92.9 ± 2.6)

  1. *p < 0.05 vs. after 10 min without MG
  2. p < 0.05 vs. after 5 h without MG
  3. aThe tablets were soaked into the warm water, suspended and treated by method I. The percentages of the quantitative values to the labeled amounts of the individual tablets were then calculated. For SS and EZ, the suspensions were also treated by method II, and the quantitative results are shown in the parentheses
  4. bThe mixtures in the 100-mL volumetric flasks were sonicated for 10 min