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Table 3 Basic characteristics of included study

From: Five years of safety profile of bevacizumab: an analysis of real-world pharmacovigilance and randomized clinical trials

Author

Year

Clinical trial number

phase

Number of experimental groups

Number of control group

Indication

Countris/Area

Age, median

Gender, male (%)

David A. Reardon

2020

NCT02017717

3

185

184

Glioblastoma

12 countries

55 (22–76)

119 (64.3)

Chiara Cremolini

2018

NCT02295930

2

69

74

Colorectal cancer

IT

59 (53‐67)

42 (74)

Ingrid U Scott

2017

NCT01969708

3

182

180

Macular edema

US

69 (15verage)

107 (58.8)

Cesare Gridelli

2018

NCT01351415

3

243

232

NSCLC

several countries

63 (26–84)

155 (63.3)

Hiroaki Akamatsu

2020

UMIN000023761

2

40

41

NSCLC

unknown

68 (41–82)

31 (47)

Marla Lipsyc-Sharf

2022

NCT02292758

2

19

17

Colorectal cancer

US

55 (48–65)

20 (55.6)

Sermsiri Sangroongruangsri

2018

TCTR20141002001

3

5975

379

Retinal disease

THA

58 (average)

3000 (47.2)

Matthew H Kulke

2022

NCT01229943

2

75

75

pNETS

unknown

56 (21–86)

84 (56)