Fig. 2

Box-and-whisker plots and Wilcoxon signed-rank tests of baseline versus follow-up bone mineral density. One patient who did not undergo follow-up BMD measurements was excluded from the analysis. Box-and-whisker plots show the median and interquartile ranges, as well as the upper and lower extremes. Diamond-shaped dots show outliers. Dot plots depict the baseline and follow-up BMD in 28 paired samples connected by a line. Paired Wilcoxon signed-rank tests were used to evaluate changes in BMD. A p-value < 0.05 indicated statistical significance. The follow-up lumbar spine BMD was significantly higher than that at baseline (median, 0.803 [IQR, 0.744–0.876] versus 0.888 [0.805–0.943]), respectively. Similarly, the follow-up femoral neck BMD was significantly higher than that at baseline (median, 0.615 [IQR, 0.569–0.661] versus 0.631 [0.584–0.708]), respectively. The median follow-up time was 658 (IQR, 501–906) days. BMD, bone mineral density; IQR, interquartile range