Table 1 ATC4, generic name, and DDD of antihypertensive drugs
Mechanism of action | ATC4*1 | Generic name | DDD*2 (g) |
|---|---|---|---|
Phosphodiesterase inhibitors | B01AC | Dipyridamole | 0.400 |
Organic nitrates | C01DA | Isosorbide mononitrate Isosorbide dinitrate | 0.040 0.060 |
Other vasodilators used in cardiac diseases | C01DX | Dilazep Nicorandil | 0.100 0.040 |
Methyldopa | C02AB | Methyldopa | 1.000 |
Alpha-adrenoreceptor antagonists | C02CA | Doxazosin Urapidil | 0.004 0.120 |
Sulfonamides, plain | C03BA | Indapamide | 0.003 |
Aldosterone antagonists | C03DA | Eplerenone | 0.050 |
Beta-blocking agents, selective | C07AB | Metoprolol | 0.150 |
Alpha- and beta-blocking agents | C07AG | Carvedilol | 0.038 |
Dihydropyridine derivatives | C08CA | Amlodipine Azelnidipine Benidipine Cilnidipine Efonidipine Nifedipine | 0.005 0.016*3 0.004*3 0.010 0.040*3 0.030 |
Phenylalkylamine derivatives | C08DA | Verapamil | 0.240 |
Benzothiazepine derivatives | C08DB | Diltiazem | 0.240 |
ACE*4 inhibitors, plain | C09AA | Enalapril Imidapril | 0.010 0.010 |
ARBs*5, plain | C09CA | Azilsartan Candesartan Irbesartan Losartan Olmesartan medoxomil Telmisartan Valsartan | 0.040 0.008 0.150 0.050 0.020 0.040 0.080 |
ARBs*5 and diuretics | C09DA | Candesartan and diuretics Losartan and diuretics Telmisartan and diuretics Valsartan and diuretics | 1 UD *6 |
ARBs*5 and calcium channel blockers | C09DB | Azilsartan and Amlodipine Candesartan and Amlodipine Irbesartan and Amlodipine Olmesartan medoxomil and Azelnidipine Telmisartan and Amlodipine Valsartan and Amlodipine Valsartan and Cilnidipine |