Table 1 Measurement results of the concentration of cyclosporine A in 2% cyclosporine ophthalmic solutions
Preparer | Filtered sample No. | Concentration (ng/mL) | Unfiltered sample No. | Concentration (ng/mL) | p-value* |
|---|---|---|---|---|---|
A | 1 | 501.83 | 1 | 546.63 | 0.011 |
2 | 429.03 | 2 | 525.77 | ||
B | 3 | 398.43 | 3 | 380.97 | |
4 | 374.00 | 4 | 465.23 | ||
C | 5 | 338.30 | 5 | 577.30 | |
6 | 641.33 | 6 | 644.13 | ||
D | 7 | 84.40 | 7 | 466.67 | |
8 | 85.13 | 8 | 509.90 | ||
E | 9 | 326.43 | 9 | 441.57 | |
10 | 286.23 | 10 | 439.20 | ||
Mean ± S.D. | 346.51 ± 170.76 | Mean ± S.D. | 499.74 ± 76.95 | ||
C.V. | 0.493 | C.V. | 0.154 |