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Table 4 Predictors of HRQoL in patients with hemophilia

From: Health-related quality of life and its associated factors among hemophilia patients: experience from Ethiopian Hemophilia Treatment Centre

Variables

EQ-5D-5L index score

EQ-VAS

β-Coeff. [95%CI]

SE

t

P-value

β-Coeff. [95%CI]

SE

t

P-value

Since the diagnosis of hemophilia

-0.011[0.001–0.023]

-0.006

2.05

0.043*

-0.265[-1.22, 0.686]

0.479

-0.55

0.582

Age

-0.020 [-0.034-, -0.007]

0.007

-3.05

0.003*

-0.974 [-1.72, 0.225]

0.377

-2.58

0.011*

Place residence (ref = Addis Ababa)

    

 Out of Addis Ababa

-0.128 [-0.248-, -0.007]

0.061

-2.10

0.038*

-5.12 [-11.87, 1.62]

3.398

-1.51

0.135

Level of education (ref = illiterate

    

 Primary school

-0.185 [-0.554, 0.185]

0.186

-0.99

0.324

1.45 [-2.50, 5.39]

1.99

0.73

0.467

 Secondary school

-0.192 [-0.568, 0.184]

0.189

-1.01

0.314

0.471 [-3.77, 4.71]

2.13

0.22

0.345

 Higher education

-0.135 [-0.529, 0.259]

0.199

-0.68

0.498

-0.017[-0.092,0.056]

0.037

-0.48

0.634

Employment status (ref = unemployed)

 Employed

0.124 [-0.113, 0.3621]

0.119

1.04

0.302

3.99 [-9.67, 17.7]

6.88

0.58

0.563

 Student

-0.008 [-0.185, 0.170]

0.089

-0.09

0.931

5.32 [ -4.75, 15.4]

5.07

1.05

0.297

Treatment taking (ref = factor 8)

 Factor 9

-0.059 [-0.200, 0.082]

0.071

-0.83

0.407

3.01 [ -5.11, 11.1]

4.08

0.74

0.464

 Plasma

-0.170 [-0.581, 0.240]

0.207

-0.82

0.412

-11.56 [ -35.3,12.2]

11.9

-0.97

0.337

Total joint involvement (ref =  < 2)

 Greater than 2

-0.003 [-0.060, 0.053]

0.028

-0.11

0.913

0.15 [ -3.09, 3.39]

1.63

0.09

0.926

Emergency in last year (ref = no)

 Yes

-0.015 [-0.128–0.097]

0.057

-0.27

0.786

-1.63 [-8.66- 5.38]

3.53

-0.46

0.644

Marital status

 Unmarried

0.05 [ -0.23- 0.334]

0.14

0.36

0.719

5.37 [-8.08- 18.8]

6.77

0.79

0.430

  1. *p-value < 0.05. CI Confidence interval, EQ-5D-5L EuroQoL life questionnaires five dimensions with five levels, EQ-VAS Quality of Life Group’s Visual Analog Scale Ref, Reference. * indicates p-value with a significant statistical association