Table 1 Cortisol and ACTH levels from before initiation to after discontinuation of pembrolizumab
Cycle of pembrolizumab | Before | 2nd | 3rd | 4th | 5th | 6th | 7th | 8th | 9th | 10th | after 11th |
|---|---|---|---|---|---|---|---|---|---|---|---|
Cortisol, µg/dL (Reference range: 6.2–18.0) | – | – | 7.4 | 11.4 | 7.5 | 9.5 | 8.9 | – | 8.4 | 9.7 | 8.1 |
ACTH, pg/mL (Reference range: 7.2–63.3) | 19.9 | – | 51.9 | 55.8 | 26.6 | 32.4 | 33.5 | – | 25.1 | 47.6 | 48.2 |