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Table 1 Number of patients with LUTS prescribed medicines that can cause LUTS

From: Prescription rate of medications potentially contributing to lower urinary tract symptoms and detection of adverse reactions by prescription sequence symmetry analysis

(a) Medicines that caused the storage symptoms

Medication class

Medicine

Prevalence n (%)

Anti-dementia drugs

Donepezil

272

14.1

Intestinal Lavage Solution

Intestinal Lavage Solution

44

2.3

Decongestants and antiallergics

Tranilast

18

1.7

Ketotifen

15

other

※

Antineoplastic agents

Cyclophosphamide

17

1.6

(b) Medicines that caused the voiding symptoms

Medication class

Medicine

Prevalence n(%)

Anti-parkinson drugs

Trihexyphenidyl

32

13.7

Biperiden

56

Amantadine

93

Levodopa/Benserazide

72

other

※

Antidepressants

Mianserin

58

13.8

Paroxetine e

119

Fluvoxamine

61

Milnacipran

29

Anxiolytics

Diazepam

95

4.9

other

※

Antipsychotics

Chlorpromazine

30

13.3

Risperidone

108

Levomepromazine

36

Sulpiride

68

other

※

Drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)

Cimetidine

34

5.6

Scopolamine butylbromide

67

other

※

Other drugs for obstructive airway diseases, inhalants

Tiotropium bromide

129

6.7

other

※

Antihistamines for systemic use

Diphenhydramine

17

3.3

Chlorpheniramine

40

other

※

Antiarrhythmics, class I and III

Cibenzoline

27

2.0

other

※

Cardiac stimulants excl. cardiac glycosides

Amezinium metilsulfate

20

4.8

Droxidopa

48

Midodrine

24

other

※

Opioids

Morphine

19

12.4

Codeine phosphate

39

Oxycodone

172

other

※

  1. ※The number of patients prescribed the drug was less than 10.