Persistence duration
a
, days, median (range)
|
Hazard ratio
b
(95 %CI)
|
|---|
Changed to generic
|
Continued brand
|
P value
|
Unadjusted
|
Adjusted
c
|
|---|
180 (14~180) | 180 (28~180) | 0.076 | 0.69 (0.44-1.08) | 0.97 (0.61-1.55) |
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aPersistence was measured as the number of continuous days from index date to discontinuation in the 180-day.
-
bCox proportional hazard model.
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cAdjusted baseline covariates included adherence in pre-index date (baseline adherence) (PDC≧80 %), duration of use of atorvastatin prior to index date, prescribing medical establishment, comorbidities such as hypertension, arrhythmia, and calcium channel blocker.
