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Table 3 Final estimates for the population pharmacokinetic parameters of digoxin

From: Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients

Population mean parameters
  CL(L/h)= (1.21+0.0532×CLcr(mL/min)) ×(1+0.787×AMD)
  (AMD = 0 for cocomitant adminstarion of amiodarone, otherwise 1)
Interindividual variance
  ω(CL)=32.2 %
Intraindividual variance
  σ=25.5 %