Table 1 DTR-QOL items and domain structure

Factor 1: Burden on social activities and daily activities

 1. My current diabetes treatment interferes with my work and activities.

 2. My current diabetes treatment limits the scope of my activities.

 3. It is difficult to find places on time for my current diabetes.

 4. My current diabetes treatment interferes with group activities and personal friendships.

 5. It is a burden getting up at a certain time every morning for my current diabetes treatment.

 6. With my current diabetes treatment, the restricted meal times are a burden.

 7. When I eat out, it is difficult to manage my current diabetes treatment.

 8. I feel like my current diabetes treatment takes away the enjoyment of eating.

 9. With my current diabetes treatment, it is hard to curb my appetite.

 10. The time and effort to manage my current diabetes treatment are a burden.

 11. I am constantly concerned about time to manage my current diabetes treatment.

 12. Pain due to my current diabetes treatment is uncomfortable.

 13. Gastrointestinal symptoms (nausea, passing gas, diarrhea, abdominal pain) due my current diabetes treatment are uncomfortable.

Factor 2: Anxiety and dissatisfaction with treatment

 14. I am bothered by weight gain with my current diabetes treatment.

 19. I have uncomfortable symptoms due to hyperglycemia (high blood glucose).

 20. I am worried about high blood glucose.

 21. I am dissatisfied that my blood glucose is unstable (high and low).

 22. I am worried that complications might get worse with my current diabetes treatment.

 23. I get anxious thinking about living while on my current diabetes treatment.

 24. I find it unbearable to think that even if I continue my current diabetes treatment, my diabetes may not be cured.

 25. I am concerned that if I continue my current diabetes treatment, the efficacy (effectiveness) may diminish.

Factor 3: Hypoglycemia

 15. I worry about low blood glucose due to my current diabetes treatment.

 16. I am scared because of low blood glucose.

 17. I am sometimes bothered by low blood glucose.

 18. Symptoms due to low blood glucose are uncomfortable.

Factor 4: Satisfaction with treatment

 26. Overall, I am satisfied with my current blood sugar control (glycemic control).

 27. With my current diabetes treatment, I am confident that I can maintain good blood glucose control.

 28. I am hopeful about the future with my current diabetes treatment.

 29. With regards to diabetes treatment, I am satisfied with current treatment methods.