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Fig. 1 | Journal of Pharmaceutical Health Care and Sciences

Fig. 1

From: PK/PD analysis of biapenem in patients undergoing continuous hemodiafiltration

Fig. 1

Multicompartment model for BIPM during CHDF. X 1, X 2 and X 3 are the amounts of drug in the central, peripheral and hemofilter compartments, respectively; V 1, V 2 and V 3 are the volumes of the central compartment, peripheral compartment and hemofilter cartridge, respectively; R inf, drug infusion rate; k 10, 30, elimination rate constants; k 12, 13, 21, rate constants connecting the compartments

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