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Table 2 Renal function and prescribed doses

From: Opioid analgesics increase incidence of somnolence and dizziness as adverse effects of pregabalin: a retrospective study

CLCr (mL/min)

N

Median of initial dose (mg/day, range)

Defined initial dose (mg/day)

Developed adverse effects

Developed adverse effects with over defined initial dose

>60

127

150 (25–450)

150

41 (32.3 %)

1 (2.4 %)

>30–≤60

55

75 (25–150)

75

17 (30.9 %)

8 (47.1 %)

≤30

13

50 (25–150)

25 or 50

5 (38.5 %)

2 (40.0 %)