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Table 3 Characteristics of patients who developed dizziness or somnolence

From: Opioid analgesics increase incidence of somnolence and dizziness as adverse effects of pregabalin: a retrospective study

Duration of pregabalin therapy

N

Developed somnolence or dizziness

 ≤2 weeks

21 (10.8 %)

8 (38.1 %)

 >2 weeks–≤1 month

30 (15.4 %)

7 (23.3 %)

 >1 month–≤2 months

36 (18.5 %)

11 (30.6 %)

 >2 months

108 (55.4 %)

37 (34.3 %)

 Median (day, range)

78 (1–740)

 

Dosage

N

Developed somnolence or dizziness

 Within the defined initial dosage range

166 (85.1 %)

52 (31.3 %)

 Over the defined initial dosage range

29 (14.9 %)

11 (37.9 %)

Concomitant drugs with pregabalin

N

Developed somnolence or dizziness

 Oral hypoglycemic drugs

28 (14.4 %)

6 (21.4 %)

 Antihypertensive drugs

55 (28.2 %)

15 (27.2 %)

 NSAID

64 (32.8 %)

15 (23.4 %)

 Opioid pain relievers

54 (27.7 %)

25 (46.3 %)

 CNS- depressants

31 (15.9 %)

9 (29.0 %)