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Table 6 Comparison of adverse reactions reported for the branded and generic drugs

From: A laboratory data-based evaluation of the efficacy and safety of generic pravastatin sodium for long-term use

Adverse reaction Case (N) Present study Package insert
Incidence (%) Incidence (%)
Increased CPK 9 0.67 Unknown
Myalgia 7 0.52 Unknown
Rash 6 0.45 0.1-1
Discomfort 3 0.22 No documentation
Myospasm 2 0.15 <0.1
Arrhythmia 1 0.07 No documentation
Increased ALP and γ-GTP 1 0.07 0.1–1
Numbness 1 0.07 <0.1
Malaise 1 0.07 <0.1
Nausea 1 0.07 <0.1
Increased AST and ALT 1 0.07 Unknown
Thrombocytopenia 1 0.07 Unknown
Anemia (decreased Hb) 1 0.07 Unknown
Weakness 1 0.07 Unknown
Vertigo 1 0.07 Unknown
  1. Creatine phosphokinase, CPK; gamma-glutamyl transferase, γ-GTP; alkaline phosphatase, ALP; aspartate aminotransferase, AST; alanine aminotransferase, ALT; hemoglobin, Hb