Table 1 Number of reports and reporting odds ratio of BRONJ stratified by gender
Dosage form | Drug name | Case | Non-case | Total | Reporting odds ratio | (95 % CI) | |
|---|---|---|---|---|---|---|---|
Intravenous | Alendronate (I.V.) | 10 | 48 | 58 | 43.7 | (22.1 − 86.4) | |
Male | 2 | 8 | 10 | 52.1 | (11.1 − 245.7) | ||
Famale | 8 | 40 | 48 | 41.9 | (19.6 − 89.6) | ||
Pamidronate | 223 | 171 | 394 | 315.0 | (256.3 − 387.0) | ||
Male | 30 | 35 | 65 | 181.9 | (111.4 − 297.0) | ||
Famale | 186 | 128 | 314 | 341.9 | (271.4 − 430.8) | ||
Zoledronate | 809 | 972 | 1,781 | 346.2 | (308.2 − 388.8) | ||
Male | 301 | 436 | 737 | 176.5 | (150.9 − 206.4) | ||
Famale | 474 | 514 | 988 | 271.4 | (236.5 − 311.4) | ||
Oral | Alendronate (oral) | 414 | 1,252 | 1,666 | 92.3 | (81.4 − 104.5) | |
Male | 22 | 146 | 168 | 31.8 | (20.3 − 49.9) | ||
Famale | 379 | 1,096 | 1,475 | 93.8 | (82.4 − 106.8) | ||
Etidronate | 16 | 21 | 37 | 160.3 | (83.5 − 307.7) | ||
Male | 3 | 4 | 7 | 156.5 | (35.0 − 699.9) | ||
Famale | 13 | 17 | 30 | 160.6 | (77.9 − 331.1) | ||
Minodronate | 45 | 558 | 603 | 17.3 | (12.7 − 23.5) | ||
Male | 4 | 49 | 53 | 17.0 | (6.1 − 47.3) | ||
Famale | 41 | 483 | 524 | 18.1 | (13.1 − 25.0) | ||
Risedronate | 152 | 721 | 873 | 48.4 | (40.3 − 58.0) | ||
Male | 18 | 81 | 99 | 46.8 | (28.0 − 78.2) | ||
Famale | 131 | 614 | 745 | 48.3 | (39.7 − 58.7) | ||