Fig. 4

X-ray powder diffraction (XRPD) patterns of the standard sample and triturates. a XRPD patterns of the crystalline atropine sulfate and lactose hydrate. Red arrow indicates the distinctive diffraction signal of the crystalline atropine sulfate. b–d XRPD patterns of the 10-, 100-, and 1000-fold triturates prepared by the wet or dry mixing methods