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Table 2 Causative microorganisms

From: Population pharmacokinetic analysis and dosing regimen optimization of penicillin G in patients with infective endocarditis

 

Total

Penicillin success

Penicillin failure

n = 21

n = 15

n = 6

Size of vegetation (mm)

11.7 ± 6.0

12.3 ± 6.3

9.8 ± 5.7

PCG MIC

0.11 ± 0.20

0.07 ± 0.02

0.21 ± 0.38

PCG trough serum concentrations (μg/mL)

7.8 ± 9.0

10.1 ± 9.8

2.2 ± 1.2

Viridans group streptococci species level not determined

4

1

3

streptococcus sanguis

5

2

3

streptococcus gordonii

4

4

0

streptococcus agalactiae

2

2

0

streptococcusmutans

1

1

0

streptococcus intermedius

2

2

0

streptococcus mitis

1

1

0

streptococcus oralis

1

1

0

streptococcus constellatus

1

1

0