Fig. 3

Receiver operating characteristic (ROC) curves for predicting risk of toxic voriconazole level on the basis of CRP (a) and Alb (b); relationships of toxic voriconazole level with CRP and Alb (c). The true-positive rate represents the proportion of true positives that are correctly classified as positive. The false-positive rate represents the proportion of true negatives that are incorrectly classified as positive. True-positive rate = true positives/(true positives + false negatives). False-positive rate = false positives/(false positives + true negatives). Closed circles represent patients with toxic voriconazole level and open circles represent patients without toxic voriconazole level. 95 % CI, 95 % confidence interval