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Table 1 Patient characteristics

From: A retrospective analysis of patient-specific factors on voriconazole clearance

 

Mean (SD)

Male/Female

50/13

Age (yr)

70.8 (11.0)

Body Weight (kg)

49.7 (9.5)

Body Mass Index (kg/m2)

19.0 (2.9)

Albumin (g/dl)a

2.7 (0.7)

Creatinine clearance (ml/min)a

67.4 (31.9)

AST (IU/L)a

32.9 (28.6)

ALT (IU/L)a

32.9 (35.9)

ALP (IU/L)a

386.6 (409.2)

γGTP (IU/L)a

103.7 (173.1)

T-Bil (mg/dl)a

0.6 (0.8)

C reactive protein (mg/dl)a

5.6 (6.4)

Daily dose (mg/day)a

273 (89.8)

Trough concentration (μg/ml)a

3.2 (2.3)

Trough concentration collection date (after initial dose)a

 

 with loading dose

9.7 (13)

 without loading dose

11.1 (9.5)

Purpose of voriconazole administration prophylaxis/treatment

3/60

Diagnosis and treatment department

 

 Hematology/Pulmonology/Rheumatology/Other

41/17/4/1

Concomitant medicationa

 

 Glucocorcicoid

28

 Macrolide Antibiotics

2

  1. aA cumulative total of 77 samples
  2. These data were collected at the time of initial voriconazole administration