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Table 3 Change of voriconazole concentration and clearance about the patient with and without glucocorticoid administration

From: A retrospective analysis of patient-specific factors on voriconazole clearance

Patient Case. 1 Case. 2 Case. 3
Pre Post Pre Post Pre Post
Glucocorticoid mPSL 62.5 mg bid - - DEX 20 mg - PSL 20 mg
Daily dose (mg/day) 300 300 200 150 400 200
Trough concentration (μg/ml) 4.03 7.85 3.37 0.5 3.22 0.1
C/D-ratio 0.82 1.6 0.88 0.17 0.43 0.03
  1. Abbreviations: mPSL methylprednisolone, DEX dexamethasone, PSL prednisolone, bid twice daily