Table 3 Change of voriconazole concentration and clearance about the patient with and without glucocorticoid administration
From: A retrospective analysis of patient-specific factors on voriconazole clearance
Patient | Case. 1 | Case. 2 | Case. 3 | |||
|---|---|---|---|---|---|---|
Pre | Post | Pre | Post | Pre | Post | |
Glucocorticoid | mPSL 62.5 mg bid | - | - | DEX 20 mg | - | PSL 20 mg |
Daily dose (mg/day) | 300 | 300 | 200 | 150 | 400 | 200 |
Trough concentration (μg/ml) | 4.03 | 7.85 | 3.37 | 0.5 | 3.22 | 0.1 |
C/D-ratio | 0.82 | 1.6 | 0.88 | 0.17 | 0.43 | 0.03 |