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Table 1 Pharmacokinetics of mianserin after a single administration to beagle dogs

From: The pharmacokinetics of mianserin suppositories for rectal administration in dogs and healthy volunteers: a pilot study

 

tmax (h)

Cmax (ng/mL)

AUC0-24 (h • ng/mL)

AUC (h • ng/mL)

Suppository (30 mg)

5.5 ± 4.3

1.3 ± 0.4

18.9 ± 1.9

29.5 ± 3.3

Oral tablets (3 × 10 mg)

0.5

8.6 ± 3.7

27.0 ± 8.6

23.8 ± 7.7

  1. Mean ± SD, n = 3