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Table 1 Pharmacokinetics of mianserin after a single administration to beagle dogs

From: The pharmacokinetics of mianserin suppositories for rectal administration in dogs and healthy volunteers: a pilot study

  tmax (h) Cmax (ng/mL) AUC0-24 (h • ng/mL) AUC (h • ng/mL)
Suppository (30 mg) 5.5 ± 4.3 1.3 ± 0.4 18.9 ± 1.9 29.5 ± 3.3
Oral tablets (3 × 10 mg) 0.5 8.6 ± 3.7 27.0 ± 8.6 23.8 ± 7.7
  1. Mean ± SD, n = 3