Table 2 Adjusted reporting odds ratio of SJS/TEN stratified by age

Total

 Reporting Year

−0.025

<0.0001^b

0.98

(0.97-0.98)

 Gender female

0.104

<0.0001^b

1.11

(1.06-1.17)

 Age

   ≤ 19 years

0.284

<0.0001^b

1.33

(1.21-1.45)

  20-39 years

0.579

<0.0001^b

1.78

(1.65-1.93)

  40–59 years^a

  60–79 years

−0.349

<0.0001^b

0.71

(0.66-0.75)

   ≥ 80 years

−0.327

<0.0001^b

0.72

(0.66-0.79)

Allopurinol

 Reporting Year

0.005

0.7756

1.00

(0.97-1.04)

 Gender female

0.630

<0.0001^b

1.88

(1.54-2.29)

 Age

   ≤ 19 years

−1.515

0.0713

0.22

(0.01-1.11)

  20-39 years

0.165

0.4712

1.18

(0.75-1.82)

  40–59 years^a

  60–79 years

−0.123

0.3285

0.88

(0.69-1.13)

   ≥ 80 years

0.073

0.6324

1.08

(0.80-1.45)

Loxoprofen

 Reporting Year

−0.027

0.0706

0.97

(0.95-1.00)

 Gender female

−0.150

0.1154

0.86

(0.71-1.04)

 Age

   ≤ 19 years

0.429

0.0751

1.54

(0.96-2.39)

  20-39 years

0.635

<0.0001^b

1.89

(1.49-2.39)

  40–59 years^a

  60–79 years

−0.535

<0.0001^b

0.59

(0.46-0.75)

   ≥ 80 years

−1.399

<0.0001^b

0.25

(0.14-0.41)

Acetaminophen

 Reporting Year

0.023

0.1744

1.24

(0.89-1.73)

 Gender female

0.287

0.0082^b

1.33

(1.08-1.65)

 Age

   ≤ 19 years

0.230

0.1292

1.26

(0.94-1.70)

  20-39 years

0.266

0.0972

1.31

(0.95-1.79)

  40–59 years^a

  60–79 years

−0.184

0.2818

0.83

(0.60-1.16)

   ≥ 80 years

−1.103

0.0004^b

0.33

(0.16-0.62)

Carbamazepine

 Reporting Year

0.005

0.7666

1.00

(0.97-1.04)

 Gender female

0.187

0.0765

1.21

(0.98-1.48)

 Age

   ≤ 19 years

0.083

0.6486

1.09

(0.76-1.55)

  20-39 years

0.360

0.0209^b

1.43

(1.06-1.95)

  40–59 years^a

  60–79 years

0.416

0.0027^b

1.52

(1.15-2.00)

  ≥80 years

−0.419

0.1293

0.66

(0.36-1.12)

Lamotrigine

 Reporting Year

0.036

0.3618

1.04

(0.96-1.12)

 Gender female

0.158

0.1978

1.17

(0.92-1.49)

 Age

   ≤ 19 years

−0.992

<0.0001^b

0.37

(0.22-0.60)

  20-39 years

−0.418

0.0034^b

0.66

(0.50-0.87)

  40–59 years^a

  60–79 years

−0.176

0.2672

0.84

(0.61-1.14)

   ≥ 80 years

0.162

0.5984

1.18

(0.63-2.09)