Table 1 Genotype distribution
No. | Gene | Localization | SNP | Exchange | N | Genotype frequencies (%) | MAF | HWE | ||
|---|---|---|---|---|---|---|---|---|---|---|
−/− | +/− | +/+ | ||||||||
1 | HTR3A | 5′ UTR | rs1062613 | C > T | 200 | 150 (75.0) | 48 (24.0) | 2 (1.0) | 0.13 | 0.64 |
2 | HTR3B | Promotor | −100_-102 AAG insertion/deletion | delAAG | 127 | 94 (74.0) | 27 (21.3) | 6 (4.7) | - | - |
3 | Exon 5 | rs1176744 | T > G | 198 | 102 (51.5) | 83 (41.9) | 13 (6.6) | 0.28 | 0.62 | |
4 | Exon 6 | Ala223Thr | G > A | 200 | 200 (100) | 0 (0) | 0 (0) | 0 | - | |
5 | HTR3C | Exon 5 | rs6766410 | A > C | 191 | 79 (41.4) | 81 (42.4) | 31 (16.2) | 0.37 | 0.80 |
6 | TACR1 | Exon 2 | Y192H | T > C | 200 | 200 (100) | 0 (0) | 0 (0) | 0 | - |
7 | Exon 4 | rs17838409 | G > A | 200 | 200 (100) | 0 (0) | 0 (0) | 0 | - | |
8 | DRD2 | Exon 7 | rs6277 | C > T | 200 | 179 (89.5) | 21 (10.5) | 0 (0) | 0.06 | 0.98 |
9 | Intron 6 | rs1076560 | C > A | 200 | 76 (38.0) | 95 (47.5) | 29 (14.5) | 0.38 | 1.00 | |
10 | COMT | Exon 4 | rs4680 | G > A | 197 | 88 (44.6) | 85 (43.2) | 24 (12.2) | 0.34 | 0.87 |