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Table 4 Amino acid sequences of the env V3-coding region of the samples with discordant coreceptor tropism predictions between plasma RNA and PBMC DNA

From: Possible involvement of distinct phylogenetic clusters of HIV-1 variants in the discrepancies between coreceptor tropism predictions based on viral RNA and proviral DNA

Patient

Compartment

V3 amino acid sequences

FPR (%)

P8

Plasma RNA

C

A

R

P

N

N

N

T

R

K

S

V

S

M

G

P

G

K

V

M

Y

A

T

G

A

I

I

G

D

I

R

Q

A

H

C

8.7

PBMC DNA

C

T/A

R

P

N

N

N

T

R

K

S

V

S

M

G

P

G

K

V

M

Y

A

T

G

A

I

I

G

D

I

R

Q

A

H

C

14.3

P10

Plasma RNA

C

T

R

P

N

N

N

T

R

K

S

I

H

I

G

P

G

R

A

F

Y

A

T

G

D

I

T

G

D

I

R

K

A

H

C

40.1

PBMC DNA

C

T

R

P

N

S

N

T

R

K

S

I

R

I

G

P

G

R

A

F

V

A

T

G

G

I

T

G

D

I

R

K

A

Y

C

1.7

P25

Plasma RNA

C

T

R

P

N

N

N

T

R

K

S

I

H

I

G

P

G

R

A

F

Y

A

T

G

D

I

I

G

E/D

I

R

Q

A

H

C

62.5

PBMC DNA

C

T

R

P

N

S

I

T

R

K

T

I

H

I

G

P

R

R

A

F

Y

A

T

R

Q/R

I

I

E

N

I

R

Q

A

H

C

14.7

P27

Plasma RNA

C

T

R

P

N

N

N

T

R

K

G

R

H

M

G

P

G

G

A

F

W

A

T

G

E

I

I

G

N

I

R

Q

A

H

C

89.1

PBMC DNA

C

T

R

P

N

N

N

T

R

K

G

I

H

M

G

P

G

G

A

F

W

A

R

G

D

I

I

G

N

I

R

Q

A

H

C

7.4

P45

Plasma RNA

C

T

R

P

N

N

N

T

I

K

S

I

H

L

G

P

G

Q

A

L

Y

T

T

-

D

I

I

G

D

I

R

Q

A

H

C

89.1

PBMC DNA

C

T

R

P

N

S

N

T

I

R

R

I

P

I

G

P

G

R

A

F

Y

T

T

G

R

I

-

G

D

I

R

Q

A

H

C

1.1

  1. Amino acids that differed between DNA and RNA samples from the same patient are indicated in bold