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Table 2 Effect of the regional cooling on the prescription of the PN therapeutic drug and PTX doses reduction due to PN

From: The effectiveness of regional cooling for paclitaxel-induced peripheral neuropathy

Cycle

Control group (n = 142)

Regional cooling group (n = 40)

p-value

Prescription of the PN therapeutic drug※

52 (36.6 %)

11 (27.5 %)

P = 0.378

PTX doses reduction due to PN

5 (3.5 %)

2 (5.0 %)

P = 0.645

  1. PN Peripheral neuropathy. The p value indicated hazard ratio of the chi-square test
  2. ※pregabalin, duloxetine hydrochloride, mecobalamin, gosha-jinki-gan, tramadol, oxycodone