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Table 3 Final pharmacokinetic parameter estimates for cefmetazole in patients undergoing colorectal surgery

From: Optimal dosage of cefmetazole for intraoperative antimicrobial prophylaxis in patients undergoing surgery for colorectal cancer

Pharmacokinetic Parameters

 CLCMZ = θ1 × Ccr

(L/h)

 VdCMZ = θ2 × BW

(L)

Estimate

 θ1

0.0704

 θ2

0.163

Variability

 ωCL (%)

21.0

 ωVd (%)

8.4

 σ (%)

13.5