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Table 5 Risk factors associated with Grade 3/4 neutropenia among 24 patients undergoing MVAC therapy at the first course, univariate logistic regression analysis

From: Co-administration of dexamethasone increases severity and accelerates onset day of neutropenia in bladder cancer patients on methotrexate, vinblastine, adriamycin and cisplatin chemotherapy: a retrospective cohort study

Variable Incidence of severe neutropenia (%) OR (95% CI) P value
Dexamethasone (+) : 94.4 17.0 (1.3–223.1) 0.03
(−) : 50.0   
Age (>65 y) (+) : 88.2 3.0 (0.33–27.2) 0.33
(−) : 71.4   
Female Female : 75.0 0.5 (0.04–7.0) 0.63
Man : 85.0   
PS (>0) (+) : 66.7 0.3 (0.02–4.9) 0.42
(−) : 85.7   
Total bilirubin (>0.5 mg/dL) (+) : 90.9 3.0 (0.3–34.0) 0.38
(−) : 76.9   
BMI (<23 kg/m2) (+) : 84.6 1.2 (0.1–10.5) 0.86
(−) : 81.8   
  1. OR odds ratio, PS performance status, BMI body mass index, CI confidence interval