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Table 1 Baseline clinical characteristics of participants

From: Drug interaction between methotrexate and salazosulfapyridine in Japanese patients with rheumatoid arthritis

Items

Participants

No. of patients (male/female)

10 (5/5)

Age (years)

64.1 ± 10.6

Duration of RA (years)

8.4 ± 11.0

Cr (mg/dL)

0.66 ± 0.12

BUN (mg/dL)

15.6 ± 4.9

AST (IU/L)

20.5 ± 3.3

ALT (IU/L)

23.3 ± 11.6

MCV (fL)

97.8 ± 2.5

CRP (mg/dL)

0.2 ± 0.2

SDAI

5.4 ± 4.0

DAS28-CRP

2.1 ± 0.8

MMP-3 (ng/mL)

130.2 ± 88.6

MTX (mg/week)

7.0 ± 3.0

MTX dosage at first dose each week

 4 mg (No. of patients)

5

 2 mg (No. of patients)

5

SASP (mg/day)

1000 ± 0

PSL (mg/day)

2.7 ± 2.7

No. of drugs being taken

6.0 ± 2.1

  1. Cr Serum creatinine, BUN blood urea nitrogen, AST aspartate aminotransferase, ALT alanine aminotransferase, MCV mean corpuscular hemoglobin, CRP C-reactive protein, SDAI simplified disease activity index, DAS28-CRP disease activity score-C reactive protein, MMP-3 matrix metalloproteinase-3, MTX methotrexate, SASP salazosulfapyridine and PSL prednisolone. Data are mean ± SD