Effective | Ineffective | P value | |
---|---|---|---|
Case, no. (%) | 105 (82.0) | 23 (18.0) | - |
Age (years)a | 77.2 ± 5.11 | 79.0 ± 4.51 | 0.10 |
Sex, no. (%) | |||
male | 25 (23.8) | 3 (13.0) | 0.40 |
female | 80 (76.2) | 20 (87.0) | |
Height (cm)b | 150 (135–176) | 145 (140–165) | 0.08 |
Body weight (kg)b | 57 (38–91) | 51 (39–69) | 0.11 |
Enoxaparin dose, no. (%) | |||
2000 mg/day | 36 (34.3) | 9 (39.1) | 0.64 |
4000 mg/day | 69 (65.7) | 14 (60.9) | |
Previous history of DVT, no. (%) | |||
yes | 4 (3.81) | 3 (13.0) | 0.11 |
Use of tourniquet, no. (%) | |||
yes | 35 (33.3) | 15 (65.2) | <0.01 |
Operative time, (min)b | 110 (65–260) | 100 (75–210) | 0.14 |
Volume of bleeding during surgery (mL)b | 100 (0–1530) | 70 (0–500) | 0.33 |
Laboratory values at POD1 | |||
Total serum protein (g/dL)a | 5.85 ± 0.60 | 6.35 ± 0.53 | <0.001 |
Serum creatinine (mg/dL)b | 0.68 (0.35–2.13) | 0.64 (0.43–1.07) | 0.15 |
BUN (mg/dL)b | 13.5 (7.4–24.3) | 12.0 (8.6–20.0) | 0.16 |
AST (IU/L)b | 20.0 (11.0–80.0) | 20.0 (11.0–44.0) | 0.68 |
ALT (IU/L)b | 13.0 (5.0–50.0) | 12.0 (6.0–57.0) | 0.50 |
LDH (IU/L)b | 199 (122–390) | 216 (134–273) | 0.20 |
ALP (IU/L)b | 185 (94–398) | 181 (122–337) | 0.78 |
γ-GTP (IU/L)b | 14 (7–460) | 13 (8–143) | 0.69 |
ChE (IU/L)b | 220 (108–401) | 231 (144–316) | 0.90 |
Total bilirubin (mg/dL)b | 0.8 (0.3–2.7) | 0.9 (0.4–1.3) | 0.74 |
WBC (103/μL)b | 90 (45–405) | 82 (62–158) | 0.57 |
Hb (g/dL)a | 10.9 ± 1.27 | 10.6 ± 1.21 | 0.28 |
Platelet (104/μL)a | 18.2 ± 5.93 | 17.7 ± 4.61 | 0.62 |
CRP (mg/dL)b | 4.57 (1.58–12) | 5.52 (1.04–14.04) | 0.41 |
Complications, no. (%) | |||
Hypertension | 72 (68.6) | 19 (82.6) | 0.21 |
Diabetes | 13 (12.4) | 2 (8.70) | 1.00 |
Dyslipidemia | 30 (28.6) | 6 (26.1) | 1.00 |
Chronic heart failure | 6 (5.71) | 0 (0.00) | 0.59 |
Cerebral vascular disease | 6 (5.71) | 0 (0.00) | 0.59 |
Concomitant drugs, no. (%) | |||
NSAIDs | 100 (95.2) | 21 (91.3) | 0.61 |
Low dose aspirin | 12 (11.4) | 2 (8.70) | 1.00 |
Clopidogrel | 2 (1.90) | 1 (4.35) | 0.45 |
Ticlopidine | 1 (0.95) | 1 (4.35) | 0.33 |
Cilostazol | 1 (0.95) | 1 (4.35) | 0.33 |
Limaprost alfadex | 5 (4.76) | 3 (13.0) | 0.15 |
Warfarin | 6 (5.71) | 1 (4.35) | 1.00 |
Raloxifene | 4 (3.81) | 2 (8.70) | 0.29 |