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Table 1 Concentrations of cyclophosphamide and fluorouracil in wipe samples from APOTECAchemo and biological safety cabinet locations

From: Performance evaluation of the compounding robot, APOTECAchemo, for injectable anticancer drugs in a Japanese hospital

  Place Sampling timing FU (ng/cm2) CPA (ng/cm2)
APOTECA chemo (Robotics) Loading area Before compounding nd nd
After compounding nd nd
Compounding area, under shelf Before compounding
After compounding
nd
nd
nd
nd
Compounding area, under dosing device Before compounding
After compounding
nd
nd
Nd
25
Scale balance Before compounding nd nd
After compounding nd nd
Gripper of robot arm Before compounding nd nd
After compounding nd 0.04
Gloves 1st After FU compounding nd -
Gloves 2nd After compounding nd nd
Bag 1 After compounding nd nd
Bag 2 After compounding nd nd
Bag 3 After compounding nd nd
Bag 4 After compounding nd nd
BSC (Manual) Inside BSC Before compounding nd nd
After compounding 12.5 nd
Gloves 1st After FU compounding nd -
Gloves 2nd After compounding nd nd
Bag 1 After compounding nd nd
Bag 2 After compounding nd nd
Bag 3 After compounding 0.15 nd
Bag 4 After compounding 1.03 nd
  1. FU Fluorouracil, CPA Cyclophosphamide, BSC biological safety cabinet
  2. nd means < 0.05 ng/cm2 for Fluorouracil; < 0.02 ng/cm2 for Cyclophosphamide