Fig. 3
From: Effect of health foods on cytochrome P450-mediated drug metabolism
Effect of representative inhibitors on P450-mediated metabolism in Ad-P450 cells. Ad-P450 cells were incubated in culture medium containing P450 substrate cocktail and each typical P450 inhibitor (furafylline [0.05–30 μM], sulfaphenazole [0.01–10 μM], ticlopidine [0.3–300 μM], quinidine [0.01–10 μM], or ketoconazole [0.01–10 μM]) for 5 h. These media were collected and metabolites were analyzed by LC-MS/MS. The activity levels are shown as means ± SD (n = 3)