Outcome | Trial, n | RD, n | Control, n | Mean Difference [95% CI] | Heterogeneity (%) | Test for the overall effect (P value) | |
---|---|---|---|---|---|---|---|
Excluding patients with type 2 diabetes | BMI (kg/m2) | 2 | 140 | 80 | −0.38 [−0.60, −0.15] | 92 | 0.001 |
BW (kg) | 2 | 140 | 80 | −0.97 [−1.61,-0.33] | 41 | 0.003 | |
Including subjects with a BMI > 25 | BMI (kg/m2) | 1 | 30 | 25 | −0.50 [−2.93,1.93] | N. A. | 0.69 |
BW (kg) | 1 | 30 | 25 | −1.50 [−5.95, 2.95] | N. A. | 0.51 | |
Excluding the RCT with the largest sample size (Li 2010) | BMI (kg/m2) | 2 | 110 | 45 | −0.30 [−0.33, −0.27] | 0 | <0.001 |
BW (kg) | 2 | 110 | 45 | −0.80 [−0.92, −0.68] | 0 | <0.001 | |
Sensitivity analysis using the fixed-effect model | BMI (kg/m2) | 3 | 170 | 105 | −0.31 [−0.33, −0.28] | 78 | <0.001 |
BW (kg) | 3 | 170 | 105 | −0.81 [−0.93, −0.69] | 0 | <0.001 |