Development and evaluation of adsorption sheet (HD safe sheet-U) using active carbon for the purpose of the preventing the contamination diffusion of urinary excreted anticancer drug

Table 2 HPLC-UV analysis condition

Anticancer drug	Column Temperature (°C)	Mobile phase (Volume%)	Flow rate (mL/min)	Detection Wavelength (nm)	Determination limit (μg/mL)
CPA	40	H₂O : CH₃CN = 75 : 25	l.0	195	5
IFM	40	H₂O : CH₃CN = 54 : 46	1.0	198	1.0
MTX	40	0.1%CH₃COOH:CH₃OH = 80:20	l.0	307	0.1
5-FU	25	10mM KH₂PO₄ :CH₃OH = 90 : 10	l.0	285	0.75
Ara-C	40	50mMPBS(pH6.8):CH₃OH = 99.5:0.5	1.0	275	0.1
GEM	40	10mMPBS(pH7.5):CH₃OH = 98:2	1.0	275	0.1
ADR	40	90% CH₃CN:50mM PBS (pH3.2) = 68 : 32	1.0	230	1.0
Epi-ADR	40	20mM PBS (pH2.0) : CH₃CN = 69 : 31	l.0	254	0.2
PTX	40	CH₃CN : H₂O : CH₃OH = 50 : 30 : 20	l.0	236	0.5
DTX	40	10mMPBS(pH3.0):CH₃CN = 50:50	1.0	230	0.1
VP-16	40	0.007%TEA, 20mMPBS (pH5.2):CH3CN:CH3OH = 63:19:18	1.0	285	0.1
CPT-11	40	50mM KH₂PO₄, 7.5mM Bu₄NBr : CH₃CN = 83 : 17	l.0	254	0.5

PBS phosphate buffer saline, Bu ₄ NBr Tetrabutylammonium bromide, TEA triethlamine

ISSN: 2055-0294