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Table 1 Characteristics of patients with Sjӧgren’s syndrome and dry mouth

From: New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life

Number of patients (male / female)

24 (0/24)

Average age (years) a

61.8 ± 13.4

Salivary secretion (g/30 s.) a

0.076 ± 0.092

Major complications (cases)

 Osteoporosis

10

 Rheumatism

7

 Hypertension

7

 Refractory gastroesophageal reflux disease

6

 Keratitis

6

 Diabetic

5

 Hyperlipidemia

5

 Systemic scleroderma

4

 Insomnia

4

Clinical laboratory tests

 Anti-SS-A b antibody (cases)

 

   > 5 U/mL

17

   < 5 U/mL

7

 IgG (cases)

 

   < 800 mg/dL

2

  800–1700 mg/dL

9

   > 1700 mg/dL

11

 Serum creatinine (mg/dL) a

0.75 ± 0.24

 Blood urea nitrogen (mg/dL) a

14.6 ± 4.6

 Aspartate aminotransferase (U/L) a

23 ± 11

 Alanine aminotransferase (U/L) a

17 ± 7

  1. a: Where indicated, data are expressed as means ± SD
  2. b: Anti-Sjögren’s syndrome-related antigen A