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Table 3 Patient characteristics and treatment status

From: Changes in tear volume and ocular symptoms of patients receiving oral anticancer drug S-1

 

Watering eyes

No watering eyes

P

n = 6

n = 5

Age

(year)

70

(44–80)

63

(43–67)

0.297*

Sex

(male/female)

6

(3/3)

5

(3/2)

1.000**

Height

(cm)

156.15

(147.0–178.0)

146.2

(154.3–164.0)

0.535*

Body weight

(Kg)

46.75

(40.0–58.8)

47.6

(31.2–78.4)

0.548*

BSA

(m2)

1.372

(1.29–1.69)

1.404

(1.16–1.79)

0.548*

Scr

(mg/dL)

0.61

(0.43–0.98)

0.6

(0.49–0.80)

0.575*

Dose

Start

(mg)

100

(80–120)

100

(80–120)

0.535*

 

Total

(mg)

13,440

(4880–19,790)

13,440

(5820–22,360)

0.548*

Therapeutic intensity

RDI

(%)

82.68

(49.11–99.41)

79.95

(54.34–95.14)

0.522*

Treatment period

Course

 

7

(2–8)

8

(2–8)

0.382*

 

Days

 

319

(84–350)

350

(91–371)

0.601*

  1. Age, height, body weight, BSA, Scr,dose, therapeutic intensity, and treatment period are indicated as median (range)
  2. Relative Dose Intensity (RDI) = [actual dose (mg)/week]/[standard dose (mg)/week]
  3. *Mann–Whitney U-test; **Fisher’s exact probability test