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Table 2 Occurrence of individual adverse events in both groups

From: Impact of pharmacist counseling on reducing instances of adverse events that can affect the quality of life of chemotherapy outpatients with breast Cancer

Adverse events n (%)   Before 1st course Before 2nd course Before 3rd course
Grade Non intervention Intervention P Non intervention Intervention P Non intervention Intervention P
Constipation 2 0 (0) 0 (0) 0.342 2 (10.5) 2 (10.0) 0.975 3 (15.8) 3 (15.0) 0.975
1 3 (15.8) 1 (5.0) 6 (31.6) 7 (35.0) 6 (31.6) 7 (35.0)
0 16 (84.2) 19 (95.0) 11 (57.9) 11 (55.0) 10 (52.6) 10 (50.0)
Nausea 2 0 (0) 0 (0) 1.000 1 (5.3) 0 (0) 0.264 0 (0) 0 (0) 0.155
1 1 (5.3) 1 (5.0) 9 (47.4) 6 (30.0) 7 (36.8) 3 (15.0)
0 18 (94.7) 19 (95.0) 9 (47.4) 14 (70.0) 12 (63.2) 17 (85.0)
Oral pain 2 0 (0) 0 (0) 1.000 0 (0) 0 (0) 0.523 0 (0) 1 (5.0) 0.490
1 0 (0) 0 (0) 9 (47.4) 7 (35.0) 6 (31.6) 8 (40.0)
0 19 (100) 20(100) 10 (52.6) 13 (65.0) 13 (68.4) 11 (55.0)
Vomiting 2 0 (0) 0 (0) 1.000 0(0) 1 (5.0) 0.126 0 (0) 0 (0) 0.342
1 0 (0) 0 (0) 5 (26.3) 1 (5.0) 3 (15.8) 1 (5.0)
0 19 (100) 20 (100) 14 (73.7) 18 (90.0) 16 (84.2) 19 (95.0)
Fever 2 0 (0) 0 (0) 1.000 2 (10.5) 1 (5.0) 0.443 0 (0) 0 (0) 0.605
1 0 (0) 0 (0) 2 (10.5) 5 (25.0) 1 (5.3) 3 (15.0)
0 19 (100) 20 (100) 15 (78.9) 14 (70.0) 18 (94.7) 17 (85.0)
Malaise 2 0 (0) 0 (0) 0.342 4 (21.1) 3 (15.0) 0.700 1 (5.3) 2 (10.0) 0.684
1 3 (15.8) 1 (5.0) 8 (42.1) 7 (35.0) 11 (57.9) 9 (45.0)
0 16 (84.2) 19 (95.0) 7 (36.8) 10 (50.0) 7 (36.8) 9 (45.0)
Anorexia 2 0 (0) 0 (0) 0.231 3 (15.8) 2 (10.0) 0.809 1 (5.3) 1 (5.0) 0.703
1 2 (10.5) 0 (0) 7 (36.8) 9 (45.0) 11 (57.9) 9 (45.0)
0 17 (89.5) 20 (100) 9 (47.4) 9 (45.0) 7 (36.8) 10 (50.0)
Peripheral sensory neuropathy 2 0 (0) 0 (0) 1.000 0 (0) 0 (0) 0.695 0 (0) 0 (0) 1.000
1 1 (5.3) 1 (5.0) 3 (15.8) 5 (25.0) 4 (21.1) 4 (20.0)
0 18 (94.7) 19 (95.0) 16 (84.2) 15 (75.0) 15 (78.9) 16 (80.0)
Alopecia 2 1 (5.3) 0 (0) 0.487 14 (73.7) 11 (55.0) 0.230 16 (84.2) 17 (85.0) 0.547
1 0 (0) 0 (0) 3 (15.8) 8 (40.0) 3 (15.8) 2 (10.0)
0 18 (94.7) 20 (100) 2 (10.5) 1 (5.0) 0 (0) 1 (5.0)
Nail ridging 2 0 (0) 0 (0) 1.000 0 (0) 0 (0) 1.000 0 (0) 0 (0) 0.748
1 2 (10.5) 3 (15.0) 3 (15.8) 4 (20.0) 11 (57.9) 13 (65.0)
0 17 (89.5) 17 (85.0) 16 (84.2) 16 (80.0) 8 (42.1) 7 (35.0)
Skin disorder 2 0 (0) 0 (0) 0.342 1 (5.3) 0 (0) 0.561 1 (5.3) 0 (0) 0.581
1 3 (15.8) 1 (5.0) 8 (42.1) 8 (40.0) 7 (36.8) 8 (40.0)
0 16 (84.2) 19 (95.0) 10 (52.6) 12 (60.0) 11 (57.9) 12 (60.0)
  1. Fisher’s exact test