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Table 4 Comparison of prognosis of elderly and non-elderly patients

From: Analyses of non-benzodiazepine-induced adverse events and prognosis in elderly patients based on the Japanese adverse drug event report database

Adverse event (High Level Group Term) RR (95%CI) χ2
Especially the prognostic comparison of AEs characterized by the elderly
 Glaucoma and ocular hypertension 0.33 (0.12–0.92) 0.32
 Impulse control disorders NEC 0.08 (0.01–1.10) 0.09
 Neurological special senses and psychiatric investigations 1.00 (1.00–1.00) NA
 Injuries by physical agents 0.33 (0.01–12.81) 0.37
 Personality disorders and disturbances in behaviour 1.91 (0.10–34.92) 0.13
 Neurological disorders of the eye 0.67 (0.27–1.63) 0.04
 Manic and bipolar mood disorders and disturbances 0.71 (0.02–25.32) 0.86
 Movement disorders (include parkinsonism) 0.35 (0.04–3.46) 0.10
 Enzyme investigations NEC 0.23 (0.02–2.73) 0.06
 Disturbances in thinking and perception 0.39 (0.01–16.90) 0.42
 Vision disorders 4.85 (0.35–66.36) 0.99
 Ocular infections irritations and inflammations 0.47 (0.21–1.00) 0.53
Prognostic comparison of other AEs
 Deliria (include confusion) 3.91 (0.22–68.39) 0.30
 Product use issues 0.67 (0.09–4.83) 0.02
 Sleep disturbances (include subtypes) 1.82 (0.23–14.26) 0.004
 Sleep disturbances 1.53 (0.33–7.13) 0.02
 Psychiatric and behavioural symptoms NEC 2.88 (0.71–11.73) 1.55
 Dementia and amnestic conditions 0.80 (0.06–11.50) 0.33
 Suicidal and self-injurious behaviours NEC 0.95 (0.48–1.89) 0.02
 Mental impairment disorders 0.87 (0.06–12.52) 0.40
 Neurological disorders NEC 1.18 (0.47–2.91) 0.01
 Psychiatric disorders NEC 0.31 (0.04–2.65) 0.46
 Respiratory disorders NEC 0.48 (0.27–0.87) 5.54
 Injuries NEC 1.20 (0.37–3.93) 0.01
 Changes in physical activity 0.80 (0.07–9.18) 0.39
 Changes in physical activity 0.80 (0.07–9.18) 0.39
 Therapeutic and nontherapeutic effects (exclude toxicity) 0.44 (0.02–9.61) 0.04
 Depressed mood disorders and disturbances 1.5 (0.13–17.67) 0.23
  1. ※AEs adverse events, RR risk ratio, 95%CI 95% confidence interval, NEC not elsewhere classified