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Fig. 8 | Journal of Pharmaceutical Health Care and Sciences

Fig. 8

From: Low concentrations of clarithromycin upregulate cellular antioxidant enzymes and phosphorylation of extracellular signal-regulated kinase in human small airway epithelial cells

Fig. 8

Effects of U0126 on cell viability in SAECs stimulated with H2O2. Cell viability was assessed by measuring formazan production from viable cells (at 450 nm) as described in the Methods. Samples were obtained from control cells, from cells pretreated with 10 μM U0126 alone for 0.5 h, or from cells pretreated with or without 10 μM U0126 for 0.5 h before stimulation with 100 μM H2O2 for 3 h. Data are presented as means ± SD of three independent experiments. **p < 0.01 vs. control cells, ##p < 0.01 vs. cells pretreated with 10 μM U0126 alone, ††p < 0.01 vs. cells pretreated without 10 μM U0126 before H2O2 stimulation (cells stimulated with H2O2 alone)

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