Safety profile of prophylactic rescue dosing of immediate-release oral opioids in cancer patients

Table 4 Comparison of the incidence of adverse events between the prophylactic and regular groups in the morphine subgroup

Adverse event	Prophylactic morphine	Regular morphine	P value
Adverse event	n = 38	n = 14	P value
Somnolence, n (%)	6 (15.8)	2 (14.3)	1.00^a
Nausea, n (%)	10 (26.3)	4 (28.6)	1.00^a
Constipation, n (%)	12 (31.6)	4 (28.6)	1.00^a
Urinary retention, n (%)	0 (0)	1 (7.1)	0.27^a
Delirium, n (%)	2 (5.3)	1 (7.1)	1.00^a
Pruritus, n (%)	0 (0)	1 (7.1)	0.27^a

ISSN: 2055-0294