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Table 5 Comparison of the incidence of adverse events between the prophylactic and regular groups in the oxycodone subgroup

From: Safety profile of prophylactic rescue dosing of immediate-release oral opioids in cancer patients

Adverse event

Prophylactic oxycodone

Regular oxycodone

P value

n = 30

n = 21

Somnolence, n (%)

8 (26.7)

3 (14.3)

0.49a

Nausea, n (%)

5 (16.7)

2 (9.5)

0.69a

Constipation, n (%)

1 (3.3)

3 (14.3)

0.29a

Urinary retention, n (%)

1 (3.3)

0 (0)

1.00a

Delirium, n (%)

1 (3.3)

2 (9.5)

0.56a

Pruritus, n (%)

0 (0)

0 (0)

1.00a

  1. aFisher’s exact test