Table 2 Comparison of demographic and clinical characteristics between the group with venous irritation and the group without venous irritation
From: Risk factors for venous irritation in patients receiving vinorelbine: a retrospective study
Variable | Group with venous irritation (n = 24) | Group without venous irritation (n = 39) | p-value | |
|---|---|---|---|---|
Age, years | Median (range) | 64 (35–73) | 65 (39–84) | 0.514b |
Sex (%) | Male | 14 (58.3) | 27 (69.2) | 0.423c |
Female | 10 (41.7) | 12 (30.8) | ||
Body surface area, m2 | Mean ± SD | 1.60 a ± 0.14 | 1.68 a ± 0.16 | 0.035d |
Body mass index, n (%) | ≥ 25 | 3 (12.5) | 9 (23.1) | 0.345c |
< 25 | 21 (87.5) | 30 (76.9) | ||
Regimen (%) | Single | 4 (16.7) | 8 (20.5) | 1c |
Combination | 20 (83.3) | 31 (79.5) | ||
CDDP administration | Yes | 18 (75.0) | 27 (69.2) | 0.776c |
No | 6 (25.0) | 12 (30.8) | ||
Department (%) | Respiratory medicine | 7 (29.2) | 19 (48.7) | 0.188c |
Surgery | 17 (70.8) | 20 (51.3) | ||
VNR dose, mg (%) | ≥ 40 | 6 (25.0) | 15 (38.5) | 0.410c |
< 40 | 18 (75.0) | 24 (61.5) | ||
Route of administration (%) | Side port | 6 (25.0) | 13 (33.3) | 0.578c |
Main route | 18 (75.0) | 26 (66.7) | ||
Drug formulation (%) | Branded | 18 (75.0) | 34 (87.2) | 0.307c |
Generic | 6 (25.0) | 5 (12.8) | ||
History of diabetes mellitus (%) | Yes | 4 (16.7) | 6 (15.4) | 1c |
No | 20 (83.3) | 33 (84.6) | ||
Dexamethasone premedication dose, mg | Mean ± SD | 10.86 ± 3.00 | 10.92 ± 3.04 | 0.946 d |
Hot compress with hot towel (%) | Yes | 8 (33.3) | 6 (15.4) | 0.124 c |
No | 16 (66.7) | 33 (84.6) | ||