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Table 2 Potential drug-related problems detected by routine pharmaceutical interventions

From: Potential drug-related problems detected by routine pharmaceutical interventions: safety and economic contributions made by hospital pharmacists in Japan

Potential drug-related problems, type and subtype

Number of cases

Improper drug selection

 Prescribing the wrong drug

30

 Duplication of drug with similar effect

140 (4)

 Contraindications (except drug interaction)

144 (3)

 Careful administration

42

 Use during pregnancy, delivery, or lactation (except contraindications)

2

 Prescription of discontinued drug

30

 Administration of stoppable drug

70

Drug interaction

 Contraindications for co-administration

24

 Precautions for co-administration

61

Overdosage

 Overdosage

585 (1)

 Dosing rate too fast

15

 Dilute concentration too high

8

Subtherapeutic dosage

 Underdosage

129 (5)

 Dosing rate too slow

11

 Dilute concentration too low

5

Inappropriate route selection

 Intravenous drug incompatibility

 

 Inappropriate solvent

26

 Inappropriate route

26

 Inappropriate use of filter

2

Improper dosing timing

 Inappropriate dosing time

55

 Lack of rest period

12

Drug use requiring therapeutic drug monitoring

 Initial dose setting

43

 Dose setting (except initial case)

63

Poor compliance

 Overuse

12

 Underuse

1

 Does not take medicine

15

 Taking a cancelled drug

4

 Inappropriate crushing or dissolution of tablets

68

 Difficulty using dosage form

60

Untreated/undertreated indications

 Necessary medication not started/restarted

117

 Omission of prescription

166 (2)

 Condition undertreated

39

 Drug must be discontinued before a test/surgery

24

 Stopping a drug that should be continued

18

Lack of monitoring by examination

 Necessary examination not performed

82

Adverse drug reactions

 Presence of serious adverse drug reactions

40

 Presence of other adverse drug reactions

99

 History of serious adverse reactions

8

 History of other adverse drug reactions

28

Consultation from doctor

 Drug selection

10

 Dosage selection

16

 Drug and dosage selection

20

 Other

6

Other

 Other

20

Overall

2,376

  1. ( ) is order of the top five potential DRP subtypes