Table 3 The numbers of cases who were reported as developing various PTs while receiving each of the glucocorticoids and RORs for the respective combinations of PTs and drugs
Drug | Case | ROR (95%CI), P value | ||||
|---|---|---|---|---|---|---|
ALL | PS + SS | ALL | PS + SS | |||
Pancreatitis acute (PT; 10033647) | ||||||
Prednisolone | 159 | 64 | 2.41 (2.06–2.82) | < 0.001 | 2.53 (1.98–3.23) | < 0.001 |
Methylprednisolone | 103 | 52 | 3.33 (2.74–4.05) | < 0.001 | 4.13 (3.14–5.42) | < 0.001 |
Dexamethasone | 133 | 76 | 1.19 (1.00–1.41) | 0.051 | 2.04 (1.63–2.56) | < 0.001 |
Pancreatitis necrotizing (PT; 10033654) | ||||||
Prednisolone | 13 | 6 | 2.02 (1.18–3.46) | 0.017 | 2.44 (1.12–5.33) | 0.040 |
Methylprednisolone | 7 | 5 | 2.32 (1.12–4.80) | 0.035 | 4.07 (1.73–9.54) | 0.009 |
Dexamethasone | 19 | 15 | 1.76 (1.12–2.76) | 0.021 | 4.18 (2.52–6.91) | < 0.001 |
Pancreatic necrosis (PT; 10058096) | ||||||
Prednisolone | 9 | 5 | 5.99 (3.12–11.51) | < 0.001 | 8.63 (3.66–20.36) | < 0.001 |
Methylprednisolone | 8 | 5 | 11.37 (5.70–22.68) | < 0.001 | 17.29 (7.33–40.80) | < 0.001 |
Dexamethasone | 2 | 1 | 0.77 (0.21–2.81) | 1.000 | 1.15 (0.20–6.55) | 0.58 |
Ischaemic pancreatitis (PT; 10066127) | ||||||
Prednisolone | 0 | 0 | NS | NS | NS | NS |
Methylprednisolone | 0 | 0 | NS | NS | NS | NS |
Dexamethasone | 2 | 2 | 98.96 (17.47–560.60) | 0.001 | 298.86 (52.75–1692.06) | < 0.001 |
Haemorrhagic necrotic pancreatitis (PT; 10076058) | ||||||
Prednisolone | 4 | 4 | 60.71 (20.42–180.51) | < 0.001 | 160.02 (53.82–475.83) | < 0.001 |
Methylprednisolone | 4 | 4 | 130.24 (43.80–387.27) | < 0.001 | 320.57 (107.80–953.33) | < 0.001 |
Dexamethasone | 0 | 0 | NS | NS | NS | NS |